Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic …
MA Cohn, I Hjelmsø, LC Wu, P Guldberg… - Nucleic acids …, 2001 - academic.oup.com
Abstract The mts1/S100A4 gene encodes a small acidic calcium-binding protein that is
expressed in a cell-specific manner in development, tumorigenesis and certain tissues of
adult mice. A composite enhancer that is active in murine mammary adenocarcinoma cells
was previously identified in the first intron of the mts1/S100A4 gene. Here we present a
detailed analysis of the structure and function of this enhancer in the Mts1/S100A4-
expressing CSML100 and non-expressing CSML0 mouse adenocarcinoma cell lines. In …
expressed in a cell-specific manner in development, tumorigenesis and certain tissues of
adult mice. A composite enhancer that is active in murine mammary adenocarcinoma cells
was previously identified in the first intron of the mts1/S100A4 gene. Here we present a
detailed analysis of the structure and function of this enhancer in the Mts1/S100A4-
expressing CSML100 and non-expressing CSML0 mouse adenocarcinoma cell lines. In …
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